Micronization of Magnolia Bark Extract with Enhanced Dissolution Behavior by Rapid Expansion of Supercritical Solution

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Micronization of magnolia bark extract with enhanced dissolution behavior by rapid expansion of supercritical solution.

A rapid expansion of supercritical solution (RESS) technology was presented for the micronization of Chinese medicinal material. Magnolia bark extract (MBE) obtained by supercritical carbon dioxide (scCO(2)) extraction technology was chosen as the experimental material. RESS process produced 4.7 microm size MBE microparticles (size distribution, 0.2-24.1 microm), which was significantly smaller...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 2010

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.58.154